News from NYU Langone Health
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In an accompanying commentary, Kathryn A. Colby, MD, PhD, the Elisabeth J. Cohen, M.D. Professor of Ophthalmology, Department of Ophthalmology, chair, Department of Ophthalmology, and Andrea Blitzer, MD, associate professor, Department of Ophthalmology, NYU Langone Health Eye Center, said eye banks can confidently use diabetic donor tissue for endothelial keratoplasty, potentially expanding supply as FDA recommendations may restrict availability. Two randomized DMEK trials presented at the American Academy of Ophthalmology meeting and published in JAMA Ophthalmology showed comparable 1 year graft success and endothelial cell loss between diabetic and non-diabetic donors, despite higher preparation failures noted by Jonathan H. Lass, MD.
µþ²â  | Becker's Spine Review
Joseph D. Zuckerman, MD, the Walter A.L. Thompson Professor of Orthopedic Surgery, and chair, Department of Orthopedic Surgery, outlines how NYU Langone Health is expanding orthopedic training, data-driven quality, and value-focused care amid rising musculoskeletal demand. The department runs the nation’s largest orthopedic residency program and multiple fellowships, supports regional growth in Brooklyn, Nassau, and Suffolk, and uses Epic dashboards for real-time outcomes and accountability. Zuckerman stresses adopting technology only when outcomes data demonstrate clear patient benefit and cost effectiveness.
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A nutritional comparison of broccoli and cauliflower highlights their similar health benefits, including fiber and micronutrients. Leah M. Kaufman, RD, dietician nutritionist, Weight Management Program, notes that while both are similar in nutrients, broccoli has a slight edge in fiber, vitamin C, and vitamin K. Cauliflower offers more folate and choline. Both cruciferous vegetables provide antioxidants and anti-cancer properties, such as sulforaphane. The article discusses their potential to cause gas due to compounds like raffinose and fructan, but concludes neither is definitively healthier, recommending consumption of both.
µþ²â  | Becker's Hospital Review
Becker’s Healthcare recognized NYU Langone Health’s Laura and Isaac Perlmutter Cancer Center among the nation’s top 20 hospitals for cancer care. The NCI-designated comprehensive cancer center provides integrated, whole-patient care, leveraging groundbreaking clinical trials, a molecular oncology center, and recent breakthroughs in therapies for lung and triple-negative breast cancers, a 580-gene diagnostic panel, and AI-supported screening innovations. Other New York-based institutions like Memorial Sloan Kettering Cancer Center and Mount Sinai also received high rankings for their oncology programs.
µþ²â  | Becker's Spine Review
Orthopedic surgeons share patient lessons that have reshaped their approaches to surgery and recovery. Vinay K. Aggarwal, MD, associate professor, Department of Orthopedic Surgery, and chief, adult reconstructive surgery service, emphasizes tailoring care to individual patient goals and fears. John G. Kennedy, MD, professor, Department of Orthopedic Surgery, chief, Division of Foot and Ankle Surgery, highlights how in-office needle arthroscopy empowers patients by allowing them to view procedures and ask questions. Joseph D. Zuckerman, MD, the Walter A.L. Thompson Professor of Orthopedic Surgery, and chair, Department of Orthopedic Surgery, notes that understanding unique patient expectations and circumstances is crucial for better outcomes. Other surgeons, including Adam Bitterman, DO, from Northwell Health, also discuss personalized recovery journeys and communication.
 
MedicalResearch.com
A study led by Michael A. Weintraub, MD, clinical assistant professor, Department of Medicine, Division of Endocrinology, Diabetes, & Metabolism, found GLP-1 receptor agonists are linked to significant benefits for dialysis patients with type 2 diabetes. The national cohort study of 151,649 patients showed GLP-1 RA use was associated with 23% lower all-cause mortality and 66% higher transplant waitlisting. Users also experienced a modest 4.03kg weight reduction. No increased risk of acute pancreatitis or thyroid cancer was observed, though diabetic retinopathy risk rose by 32%. Researchers recommend randomized controlled trials to support these real-world findings.
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Researchers at NYU Langone Health report that home-based transcranial direct current stimulation combined with mindfulness reduced cannabis use among women with multiple sclerosis. Leigh E. Charvet, PhD, professor, Department of Neurology, led a 47-participant trial showing significant four-week reductions and improved cognition and mood sustained at three months. Remote supervision and daily telehealth contact supported adherence. Ongoing pilots test general population applicability and mechanisms to guide scaling across addiction care.
News Medical
An ECOG-ACRIN phase 3 trial reported pembrolizumab after surgery did not significantly improve recurrence-free survival in Merkel cell carcinoma but cut the risk of distant metastases by 42%. After two years, 73% on pembrolizumab had no recurrence versus 66% with observation. Janice Mehnert, MD, professor, Department of Medicine, Division of Hematology and Medical Oncology, Perlmutter Cancer Center, led the study. Supported by NCI through the National Clinical Trials Network, results will be presented at ESMO 2025 on 20 October in Berlin. Overall survival follow-up continues.
µþ²â Arthur Caplan | STAT
In an opinion piece, Arthur L. Caplan, PhD, the Drs. William F. and Virginia Connolly Mitty Professor of Bioethics, Division of Medical Ethics, Department of Population Health, argues against a total ban on gestational surrogacy, despite growing international opposition from religious groups and feminists. Caplan highlights the practice as the only option for many infertile women and discusses the ethical complexities of both altruistic and commercial surrogacy, particularly in unregulated international markets and inconsistent US state laws. He advocates for minimal mandatory regulation, including licensing for surrogates, transparent agency practices, and fair compensation, to prevent exploitation and ensure legal paths to parenthood remain open.
WKTV-TV (Utica,NY)
A new study in the medical journal "Paediatrics" shows a major decrease in the number of children with food allergies over the last decade. It is all attributed to landmark research that encouraged parents to introduce small amounts of foods like peanuts to infants instead of avoiding them entirely. Purvi S. Parikh, MD, clinical assistant professor, Department of Pediatrics, Division of Pediatric Allergy & Immunology, and Department of Medicine, Division of Infectious Diseases, Allergy and Immunology, explains that there was a study done over a decade ago that found that by introducing peanuts and other high-risk allergens early, meaning between 4 to 6 months, it would prevent the development of allergies. They modelled this after other countries that introduce peanuts early, and they found that this was the case compared to a placebo, as the kids who got the peanuts early were much less likely to develop food allergy. The current recommendation is that children should be introduced not just to peanuts but to the other high-risk allergens as well.
