News from NYU Langone Health
Molecular Signatures Reveal Delayed Pig Organ Rejection. (Scientist)
(8/26) Valentin Goutaudier and colleagues at the Paris Institute for Transplantation and Organ Regeneration, in collaboration with Robert Montgomery, MD, DPhil, the H. Leon Pachter, MD, Professor of Surgery, chair, Department of Surgery; NYU Langone Transplant Institute, have developed molecular platforms to evaluate organ rejection in xenotransplantation, finding delayed immune responses in pig-to-human transplants that may be treated with inhibitor drugs.
(8/26) A genetically modified pig lung functioned for nine days in a human recipient in China, according to a study in Nature Medicine, a finding Adam Griesemer, MD, associate professor, Department of Surgery, Division Hepatobiliary and Pancreatic Surgery, NYU Langone Transplant Institute, senior member of the xenotransplant team and surgical director of the pediatric and living liver transplant programs for the NYU Langone Transplant Institute, noted warrants further research.
Also reporting on the pig lung transplantation are (8/26) and (8/26).
It Takes ѵ A Year To Get Epilepsy Under Control For Most, Study Says. (US News & World Report)
(8/26) A new study published in JAMA Neurology reveals that it typically takes about a year for individuals with focal epilepsy to achieve relief from seizures through anti-seizure medications, with 60% eventually becoming seizure-free after the right drug regimen is established; however, 63% experience ongoing or worsening seizures in the first year, and 23% have treatment-resistant epilepsy; Jacqueline A. French, MD, professor, Department of Neurology, Comprehensive Epilepsy Center, said, “Our results show that the best way to a new treatment plan is sometimes through making better use of the tools we already have instead of always searching for the next breakthrough drug.”
Also reporting is (8/26).
A Small Change In How You Walk May Help Reduce Knee Pain. (Washington Post)
The (8/27) A study involving researchers from NYU Langone Health found that altering walking gait may alleviate knee arthritis pain, with benefits comparable to over-the-counter pain medications; however, personalized lab feedback is crucial as individual responses vary, and the results are not generalizable.
Study Reveals Maui Wildfires’ True Death Toll. (CBS News Streaming Network)
(8/26) Michelle Nakatsuka, medical student and co-author of a new study, discussed the devastating impact of the 2023 Maui wildfires, which resulted in 102 deaths according to the CDC, by analyzing all-cause excess mortality, defined as the difference between observed and expected deaths during August 2023.
Eli Lilly’s Weight Loss Pill Orforglipron Clears Its Latest Trial, Paving Way For Approval. (CNBC)
(8/26) Eli Lilly’s oral weight loss pill, orforglipron, met its primary goals in a late-stage trial for patients with obesity and Type 2 diabetes, paving the way for global regulatory approval, with Howard Weintraub, MD, clinical professor, Department of Medicine, the Leon H. Charney Division of Cardiology, Center for the Prevention of Cardiovascular Disease, saying that orforglipron “may not be the answer” for morbidly overweight patients, but “for a lot of people who need to lose a fair amount of weight, losing 10% can make a big difference.”
Psilocybin Plus Meaning-Centered Psychotherapy Eases Cancer Depression. (HCPlive)
(8/26) A recent study from NYU Langone Health revealed that psilocybin, combined with psychotherapy for cancer patients, significantly reduced anxiety, depression, obsessive thoughts, anger, and physical symptoms related to psychological distress, with effects lasting up to six months; a new study investigated the use of meaning-centered psychotherapy alongside psilocybin-assisted therapy for patients with cancer and major depressive disorder.
DecisionDx-SCC Predicts Recurrence, Guides Imaging In Squamous Cell Carcinoma. (Cancer Network)
(8/26) Castle Biosciences has announced that two new studies published in SKIN The Journal of Cutaneous Medicine support the use of the DecisionDx-SCC test for predicting local recurrence and metastasis in patients with NCCN high-risk cutaneous squamous cell carcinoma (SCC); Désirée Ratner, MD, clinical professor, the Ronald O. Perelman Department of Dermatology, said, “These new data indicate that DecisionDx-SCC test results provide individualized risk predictions that doctors can use to guide risk-aligned escalation or de-escalation of care in their patients with NCCN high-risk SCC.”
Also reporting was (8/25).
7 High-Protein Meats For Muscle Growth And Other Health Benefits. (TODAY)
(8/26) Dietitians discuss the healthiest high protein meats, with Collin J. Popp, PhD, assistant professor, Department of Population Health, saying, “It’s best to distribute your protein evenly throughout the day,” adding that turkey breast is a nutritious and lean source of high-quality protein.
Trump’s Hand Bruise Renews Attention To His Health. (STAT)
(8/26)* President Trump’s health, particularly his cardiovascular condition, has gained attention following the disclosure of his chronic venous insufficiency (CVI) diagnosis, a condition affecting approximately 2.5 million Americans and characterized by symptoms like swollen legs, according to Gregory A. Magee, MD, chief, and clinical professor, Department of Surgery, Division of Vascular and Endovascular Surgery, who described CVI as a common issue treatable with low-tech methods such as compression stockings.
9 Foods For Constipation That Will Help You Poo. (Glamour (UK))
(8/26) Lisa Ganjhu, DO, clinical professor, Department of Medicine, Division of Gastroenterology and Hepatology, discussed chronic constipation, which can lead to long-term health issues like cardiovascular disease and bowel cancer, and emphasized dietary changes as a remedy, including high-fiber foods such as legumes, chia seeds, raspberries, prunes, avocados, apples, pears, whole grains, and fermented foods, which promote gut health by adding bulk to stool and introducing probiotics.
Hawai’i Keiki Museum Invites Big Island Community To Learn ѵ Project HEATWAVE: Big Island Now. (Big Island (HI) Now)
(8/26) Anna Bershteyn, PhD, associate professor, Department of Population Health, will lead a seminar discussing the project’s first year, which integrates climate modeling, public health analysis, and medical innovation to address heat wave-related health risks.
News from NYU Langone Hospital—Brooklyn
Warning Stroke: What It Is And Symptoms To Look For. (BuzzFeed)
(8/26) Strokes are a major cause of death in the U.S., with nearly 800,000 incidents annually, and Brandon Giglio, MD, clinical assistant professor, Department of Neurology, NYU Langone Hospital—Brooklyn, said that approximately 85% are ischemic strokes, while 15% are hemorrhagic; transient ischemic attacks, or warning strokes, are crucial to recognize as they can precede full strokes, and Dr. Giglio described them as “a harbinger in many people for someone who is going to have a stroke even within the next 48 hours and certainly within the next seven, 30, 90 days.”
